LeBron James

When the game is on the line, put the ball in the hands of a generational playmaker. Tied on the final possession of an overtime matchup against the Charlotte Bobcats, LeBron James studies his defender at the top of the key before pulling up and draining the first game-winner of his NBA career. In addition to the milestone jumper, the Cleveland Cavaliers star racked up 37 points, 11 rebounds and 12 assists in the March 22, 2006 matchup.